O se suʻesuʻega fou ua faʻaulutalaina "Faʻaaogaina Pix-2-Pix GAN mo Aʻoaʻoga loloto-Faʻavae-Tutoatoa PSMA PET / CT Faʻasaʻo Faʻasaʻo" na faʻasalalau talu ai nei i le Volume 15 o Oncotarget i le aso 7 o Me, 2024.
O le faʻaalia o le radiation mai suʻesuʻega PET / CT faʻasolosolo ile tulitatao o maʻi oncology o se popolega. I lenei suʻesuʻega talu ai nei, o se vaega o tagata suʻesuʻe e aofia ai Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, ma Stephanie A. Harmon mai le National Cancer Institute i le National Institutes of Health na faʻalauiloaina se meafaigaluega faʻapitoa (AI). O lenei meafaigaluega e faʻamoemoe e faʻatupuina ata PET (AC-PET) faʻasaʻo faʻasaʻo mai ata PET (NAC-PET) e le faʻasaʻoina, e ono faʻaitiitia ai le manaʻomia mo suʻega CT maualalo.
"O ata PET faʻatupuina ai Ai e iai le malosi faʻapitoa e faʻaitiitia ai le manaʻomia mo le faʻasaʻoina o le faʻamaʻi i luga o le CT scans aʻo faʻasaoina faʻailoga faʻatusatusa ma ata lelei mo tagata mamaʻi kanesa prostate."
Metotia: O se fa'ata'ita'iga loloto a'oa'oga fa'avae ile 2D Pix-2-Pix generative adversarial network (GAN) fa'ata'ita'iga na atia'e e fa'atatau ile va'aiga AC-PET ma le NAC-PET ata. O le 18F-DCFPyL PSMA (Prostate-specific membrane antigen) PET-CT suʻesuʻega o le 302 tagata gasegase e maua i le kanesa prostate na vaevaeina i aʻoaʻoga, faʻamaonia, ma faʻataʻitaʻiga vaega (n 183, 60, ma 59, faasologa). O le faʻataʻitaʻiga na aʻoaʻoina i le faʻaaogaina o taʻiala faʻapitoa e lua: Tulaga Faʻatatau (SUV) faʻavae ma SUV-NYUL faʻavae. Sa su'esu'eina le fa'ata'ita'iina o fa'atinoga fa'ata'atia i le fa'aogaina o le fa'asologa masani o le fa'ailoga sikuea (NMSE), mean absolute error (MAE), structural similarity index (SSIM) ma le pito maualuga o le fa'ailo-i-piso (PSNR). O le foma'i fa'aniukilia fa'afoma'i na fa'ataunu'uina se su'esu'ega o le tulaga o manu'a o le vaega o lo'o fiafia iai. O fa'ailoga SUV na su'esu'eina i le fa'aogaina o le fa'asoa fa'atasi i totonu o vaega (ICC), fa'asologa o le toe fa'aleleia (RC), ma fa'ata'ita'iga fa'afefiloi fa'atasi.
I'uga：I totonu o le suʻega tutoʻatasi, o le NMSE, MAE, SSIM, ma le PSNR median e 13.26%, 3.59%, 0.891, ma le 26.82, i le faasologa. O le ICC mo SUVmax ma SUVmean o le 0.88 ma le 0.89, e faʻaalia ai se faʻamaopoopo malosi i le va o faʻailoga faʻataʻitaʻiga muamua ma AI. O mea taua e pei o le nofoaga o le lesion, density (Hounsfield units), ma le lesion uptake na maua e a'afia ai le mea sese i totonu ole fua ole SUV (uma p <0.05).
"O le AC-PET na faia e le Pix-2-Pix GAN faʻataʻitaʻiga faʻataʻitaʻiga SUV metrics e vavalalata vavalalata ma ata muamua. O ata PET na gaosia e AI o loʻo faʻaalia ai le malosi o le falemaʻi mo le faʻaitiitia o le manaʻomia o suʻesuʻega CT mo le faʻasaʻoina o le faʻamaʻi aʻo faʻamautu faʻailoga faʻailoga ma ata lelei.
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E pei ona tatou iloa uma, o le atinaʻeina o le falemaʻi faʻataʻitaʻiga e le mavavaeeseina mai le atinaʻeina o se faʻasologa o mea faʻafomaʻi - faʻaeseesega faʻamaʻi faʻamaʻi ma a latou mea faʻaaoga lagolago - o loʻo faʻaaogaina lautele i lenei matata. I totonu o Saina, lea e taʻutaʻua mo lona gaosiga o gaosiga, e tele tagata gaosi oloa taʻutaʻua i le fale ma fafo mo le gaosiga o meafaigaluega faʻafomaʻi, e aofia aiLnkMed. Talu mai lona fa'avaeina, LnkMed o lo'o taula'i i luga o le fanua o fa'a'ese'ese fa'aoso maualuga injectors. O le vaega fa'ainisinia a LnkMed e ta'ita'ia e se Ph.D. ma le sili atu ma le sefulu tausaga o le poto masani ma o loʻo faʻatino loloto i suʻesuʻega ma atinaʻe. I lalo o lana taitaiga, o leCT tui tasi ulu,CT lua ulu injector,Injector sui fa'atusatusa MRI, maAngiography fa'a'ese'ese fa'a'ese'ese mea fa'asu'iua mamanuina i nei foliga: o le tino malosi ma le faʻapipiʻi, o le faʻaogaina faigofie ma le atamai faʻaoga, o galuega atoatoa, saogalemu maualuga, ma le mamanu umi. E mafai fo'i ona matou tu'uina atu tui ma paipa e fetaui ma na ituaiga ta'uta'ua o CT,MRI,DSA injectors Fa'atasi ai ma o latou uiga fa'amaoni ma le malosi fa'apolofesa, o tagata faigaluega uma a LnkMed e vala'aulia fa'atasi oe e sau e su'esu'e fa'atasi maketi.
Taimi meli: Me-14-2024
